ea0022p639 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010
Olarescu Cristina
, Husby Oystein
, Heck Ansgar
, Ringstad Geir
, Ramm-Pettersen Jon Terje
, Jorgensen Anders Palmstrom
, Bollerslev Jens
Background: Surgery is accepted as first line treatment of somatotroph macroadenomas with involvement of the optic chiasm. However, during recent years somatostatin analogues (SA) have increasingly been used as primary treatment improving ultimate cure rate, as SAs have anti-proliferative effects in most tumours. We demonstrate here positive effect of subacute/acute SA treatment on tumour shrinkage and chiasm decompression in two recently diagnosed acromegalic patients.<...